Tag Archives: metagenomics

Mock the Metagenome. Author Q&A with Nick Loman & Sam Nicholls

- May 15, 2019

mock metagenome

The mock metagenome, MAGs and breaking the first rule of Long Read Club Out today in GigaScience is a new “mock metagenome” Data Note from the Nick Loman lab in Birmingham showcasing the latest long-read sequencing technologies from Oxford Nanopore. Having published the first nanopore E. coli genome with us in 2014 showcasing the then […]

Continue reading

0 comments

Meet the GigaScience ICG Prize Winner, Pt. 2: Lisa Johnson Q&A

- December 14, 2018

ICG prize winner

Yesterday we published the winning paper of the second GigaScience prize, with additional detail and coverage in GigaBlog describing why we and the judging panel found it so novel. This was an impressively case study in reproducibility, reassembling & reannotating around 700 microbial eukaryotic transcriptomes to demonstrate this approach can aid in revealing new biologically relevant […]

Continue reading

0 comments

Reprocessing the Microbial Genomic Goldmine: Winner of the ICG13 Prize

- December 13, 2018

Microbial goldmine

Out today is the winner of our ICG13 Prize, presenting work that can aid in revealing new biologically relevant findings and missed genes from previously generated transcriptome assemblies. Teaching old data new tricks, and maximising every last nugget of information from previously funded research. Here we present some insight into why the reviewers and judges […]

Continue reading

0 comments

Making sense of pangenome networks

- October 15, 2018

Navigating Pangenome’s Labyrinth In the two decades since the first genomes were sequenced, with the exponential growth of new and closely related genomes it has become increasingly difficult to visualise and compare their structure. Particularly with the large diversity and difference in genes within microbial genomes. A new computational pipeline, published in GigaScience, makes it […]

Continue reading

0 comments

Of Mice and Men (and Monkey) Microbiomes.

- August 31, 2018

Monkey microbiome

Monkey Microbiome Business Research just out in GigaScience introduces the macaque monkey to the microbial gene catalogue club, joining other important model organisms including the (also recently published in GigaScience) Rat, Mouse, Pig and Cow. To explain more, in this posting we give some insight into what this data shows, and how this growing library […]

Continue reading

0 comments

Reproducible Research Resources for Research(ing) Parasites

- June 3, 2016

Two new research papers on scabies and tapeworms published today showcase a new collaboration with protocols.io. This demonstrates a new way to share scientific methods that allows scientists to better repeat and build upon these complicated studies on difficult-to-study parasites. It also highlights a new means of writing all research papers with citable methods that can be updated over time.

Continue reading

0 comments

Fermenting a Reproducible Research Revolution

- July 30, 2015

With greater awareness in the difficulties in making scientific research more reproducible, numerous technical fixes are being suggested to move publishing away from static and often un-reproducible papers to more reproducible digital objects that better fit 21st century technology. New research demonstrates one potential approach through publishing open data and code in containerized form using docker, and also allowing scientists to tackle climate change, through better understanding of the production of biofuels.

Continue reading

1 comment

New GigaDB Dataset: Ever wondered whats in your gut?

- July 7, 2014

A paper published in Nature Biotechnology today reveals the most comprehensive catalogue of genes in any single microbiome to date. While the roughly 20,000 genes in the human genome have been available for over a decade, the gene catalogue of the microbiome, our much larger “other genome” has to date been much more poorly understood […]

Continue reading

2 comments

Guest posting: Let’s crowdfund a fern genome that will blow your mind

- June 16, 2014

Following our efforts encouraging open-science projects, such as the community funded “Peoples Parrot” and OpenAshDieback, today we have a guest posting from Fay-Wei Li and Kathleen Pryer from the Department of Biology at Duke University covering a crowdfunding effort to sequence the Azolla genome.  They have already raised over $4,000 and have 25 days remaining until […]

Continue reading

8 comments

Moving pictures of the Microbiome in GigaScience

- November 27, 2013

Visualizations are becoming increasing important to graphically illustrate, understand, and glean insight from the explosion of larger and larger datasets in this supposed era of “big data”. Microbial ecology and the study of the microbiome is revolutionizing how we look at health, microorganism diversity and ecological interactions, but these studies are proving challenging to deal […]

Continue reading

2 comments